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Finding the right hybrid strain for you

What are hybrid strains? 

Hybrid strains are what you get when you cross indica and sativa strains, resulting in a cannabis plant variety that’s known for its balance of relaxing and uplifting effects. Hybrid plants can be indica dominant, sativa dominant, or perfectly balanced (50/50) — this will influence the type of high you experience. You might feel increased energy and a boost in mood, followed by relaxation and sedentary bliss. Because of the combination of indica and sativa effects, hybrid users report enjoying hybrid strains for daytime sessions and as a nightcap.

How to pick a hybrid strain

To pick a hybrid strain that works for you, decide what you want first.

  • Your taste: Each hybrid strain has its own aroma and flavor profile — whether you prefer sweet dessert strains or pungent skunk strains

  • Desired effects: Decide how you want to feel. Indica-dominant hybrid strains tend to be more sedating, while sativa-dominant hybrid strains are usually more stimulating

  • Strength: Check the amount of THC in the hybrid strain you’re trying. How much you need to consume to achieve your high will depend on the strain’s THC content and how new you are to using cannabis, among other factors

  • Your way: There are different ways to get high. Pick your preferred method, whether that’s smoking flower, vaping, or eating an edible

Now that you know what you’re looking for, it’s time to explore your options. Getting hybrid recommendations from a cannabis industry professional, dispensary staff, or medical marijuana doctor can help you narrow down your search and understand any potential side effects. If you’re eager to get started, trial and error is an option, too.

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The information contained in this site is provided for informational purposes only and should not be construed as medical or legal advice. Weedmaps makes no representation that the content contained here is current, accurate, or without errors. This page was last updated on June 13, 2025.

Frequently asked questions

While hybrid strains can go either way — depending on whether it’s an indica-dominant strain or a sativa-dominant hybrid strain — they usually offer a mix of energizing and sedating effects.

Hybrid strains are known to produce both uplifting and relaxing effects. Users report feeling a head high and an energy boost, followed by a relaxing body high.

Hybrid strains may be a better choice if you want to feel a balance of uplifting and calming effects rather than one or the other. 


Indica may be what you're looking for if you want to chill out or have a nightcap session. 


Sativa may be a good option if you want a little extra energy.


Hybrid strains are the most common type of strain compared to indica and sativa strains. This is because they are easier to cultivate, and breeders' crossbreeding techniques tend to produce more hybrid strains.

A strain’s taste and smell depend on its dominant terpene. For example, if the strain’s dominant terpene is limonene, you can expect more citrus fruit notes like lemons and oranges. If the dominant terpene is myrcene, you’ll pick up stronger, earthier notes, and if it’s pinene, the strain will have more herbal notes, like rosemary and mint.

Household-name hybrid strains include Sour Diesel, Wedding Cake, OG Kush, Blue Dream, and Girl Scout Cookies. They’re popular for a reason — users report these strains have the perfect balance of effects that keep them coming back.

Not necessarily. The intensity depends more on THC levels than strain type. Hybrid strains, as well as indica strains, generally have lower THC levels than sativa strains, so they might not get you as high as a sativa strain. Plus, your own tolerance plays a big role — everyone’s body responds to cannabis differently.